'
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.4
USERS' SCORE
Good
Based on 127 Reviews
8.7
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Saccharomyces boulardii(an S. cerevisiae Strain)
250 mg(5 Billion CFU)
MOS Yeast Fraction(Min. 35% Manno-oligosaccharides [MOS]) (S. cerevisiae)
200 mg

Top Medical Research Studies

9.5
Saccharomyces cerevisiae improves IBS symptoms
Saccharomyces cerevisiae for abdominal pain and discomfort in irritable bowel syndrome patients.
Relevant for IBS treatment options
We explored how Saccharomyces cerevisiae affects patients with irritable bowel syndrome (IBS). In a study involving thirty participants, we administered 500 mg capsules of this yeast twice daily for four weeks. Weekly evaluations showed significant improvements in abdominal pain and general quality of life, with notable reductions in pain scores and enhancements in various aspects of daily living. This suggests Saccharomyces cerevisiae could be a valuable treatment option for alleviating IBS symptoms.
Read More
9
Saccharomyces cerevisiae reduces IBS symptoms
Efficacy of Saccharomyces cerevisiae CNCM I-3856 as an add-on therapy for irritable bowel syndrome.
High relevance for IBS treatment
We conducted a study to assess the effectiveness of Saccharomyces cerevisiae CNCM I-3856 in treating irritable bowel syndrome (IBS). Using a randomized, placebo-controlled design, 100 newly diagnosed IBS patients received either the yeast or a placebo alongside standard treatment for 8 weeks.

We found significant reductions in abdominal pain and improved stool consistency in patients taking S. cerevisiae compared to the placebo group. All subgroups, including IBS-D, IBS-C, and IBS-M, showed notable benefits without serious adverse events.

Our findings suggest that S. cerevisiae can be a promising add-on therapy for IBS relief.
Read More
8
Probiotic shows promise for IBS-C
I-3856 in irritable bowel syndrome with predominant constipation.
Important clinical insights provided
We explored the impact of the probiotic I-3856 on managing irritable bowel syndrome with predominant constipation (IBS-C) through a thorough eight-week randomized, double-blind study involving 456 participants.

The findings showed that 45.1% of those taking I-3856 reported significant relief from abdominal pain compared to 33.9% in the placebo group. While I-3856 improved quality of life scores, the study did not demonstrate significant changes in bowel movement frequency.

Overall, I-3856 shows promise in alleviating abdominal pain and enhancing quality of life for those suffering from IBS-C.
Read More

Most Useful Reviews

9.5
Effective alternative
Jarrow Formulas saccharomycetes do not settle in the intestines but pass through the gastrointestinal tract unscathed, offering a healing effect. It effectively treats acne, diarrhoea, irritable bowel syndrome, and enhances nutrient absorption. Completely safe, I take it with me on journeys instead of bacterial probiotics. Highly recommended!
Read More
8.8
Reversed symptoms
Seven years ago, I had an ulceration in my lower colon, resulting in hospitalisation and mega doses of antibiotics, yet I battled gastrointestinal issues for years. After much research, I discovered my issues were linked to iron overload and an entirely devastated gut flora. After donating blood and starting Jarrow Formulas Saccharomyces Boulardii alongside another high-quality probiotic, I can happily say my IBS symptoms have largely reversed. I recommend this approach if you’re having similar unresolved issues.
Read More
9.5
Effective interaction
S. boulardi is not a typical probiotic; it is a yeast-like fungus that travels through the intestines, helping to curb pathogenic growth and restore normal flora. Its use is beneficial during antibiotic treatment and for those suffering from irritable bowel syndrome.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.4
9.5
Saccharomyces cerevisiae improves IBS symptoms
Saccharomyces cerevisiae for abdominal pain and discomfort in irritable bowel syndrome patients.
Relevant for IBS treatment options
We explored how Saccharomyces cerevisiae affects patients with irritable bowel syndrome (IBS). In a study involving thirty participants, we administered 500 mg capsules of this yeast twice daily for four weeks. Weekly evaluations showed significant improvements in abdominal pain and general quality of life, with notable reductions in pain scores and enhancements in various aspects of daily living. This suggests Saccharomyces cerevisiae could be a valuable treatment option for alleviating IBS symptoms.
Read More
9
Saccharomyces boulardii benefits IBS model
Saccharomyces boulardii CNCM I-745 supplementation reduces gastrointestinal dysfunction in an animal model of IBS.
High relevance for IBS treatment
We explored how Saccharomyces boulardii CNCM I-745 influences gastrointestinal issues related to irritable bowel syndrome (IBS) using a mouse model. By inoculating mice with Herpes Simplex Virus type 1 to simulate IBS symptoms, we found that the probiotic improved gut motility and reduced inflammation. After four weeks of treatment, the probiotic not only enhanced intestinal movement but also restored nerve structure integrity and decreased harmful cytokine levels. Overall, Saccharomyces boulardii shows promise in addressing IBS-like symptoms in our animal study.
Read More
9
Saccharomyces cerevisiae alleviates IBS-D
The effects of on rat colonic hypermotility induced by repeated water avoidance stress and the potential mechanism.
Significant therapeutic potential observed
We investigated how saccharomyces cerevisiae affects gut motility in rats undergoing repeated water avoidance stress, simulating diarrhea-predominant irritable bowel syndrome.

The study revealed that treatment with saccharomyces cerevisiae significantly reduced excessive defecation and colonic hypermotility. We noted improvements in the contractile activity of colonic muscles, along with changes in immune responses and gut microbiota diversity.

Overall, saccharomyces cerevisiae showed promise for alleviating symptoms associated with IBS-D by addressing both gut motility and inflammation.
Read More
9
Saccharomyces cerevisiae reduces IBS symptoms
Efficacy of Saccharomyces cerevisiae CNCM I-3856 as an add-on therapy for irritable bowel syndrome.
High relevance for IBS treatment
We conducted a study to assess the effectiveness of Saccharomyces cerevisiae CNCM I-3856 in treating irritable bowel syndrome (IBS). Using a randomized, placebo-controlled design, 100 newly diagnosed IBS patients received either the yeast or a placebo alongside standard treatment for 8 weeks.

We found significant reductions in abdominal pain and improved stool consistency in patients taking S. cerevisiae compared to the placebo group. All subgroups, including IBS-D, IBS-C, and IBS-M, showed notable benefits without serious adverse events.

Our findings suggest that S. cerevisiae can be a promising add-on therapy for IBS relief.
Read More
8
Saccharomyces boulardii may aid IBS
Serotoninergic Mechanisms of Action in the Relaxant Properties of Saccharomyces boulardii CNCM I-745 on the Intestine.
Relevant to IBS treatment effectiveness.
We explored how Saccharomyces boulardii CNCM I-745 impacts intestinal motility, particularly in the context of irritable bowel syndrome (IBS) with diarrhea. Using isolated rat ileum, we observed that S. boulardii can significantly reduce contractions induced by serotonin, suggesting it helps to regulate bowel movements.

This probiotic appears to work by inhibiting serotonin-induced contractions, providing insight into its potential effectiveness for those suffering from IBS. However, it didn’t influence contractions caused by acetylcholine, indicating a targeted action on serotonin pathways.
Read More

User Reviews

USERS' SCORE
Good
Based on 127 Reviews
8.7
9.5
Effective alternative
Jarrow Formulas saccharomycetes do not settle in the intestines but pass through the gastrointestinal tract unscathed, offering a healing effect. It effectively treats acne, diarrhoea, irritable bowel syndrome, and enhances nutrient absorption. Completely safe, I take it with me on journeys instead of bacterial probiotics. Highly recommended!
Read More
9.5
Effective interaction
S. boulardi is not a typical probiotic; it is a yeast-like fungus that travels through the intestines, helping to curb pathogenic growth and restore normal flora. Its use is beneficial during antibiotic treatment and for those suffering from irritable bowel syndrome.
9.5
Digestive improvement
After suffering from rotavirus, I began taking boulardii, which significantly improved my digestion and bowel function. It's also crucial during antibiotic use, as it maintains gut health and supports overall immunity. Highly effective and safe; I always keep a jar on hand.
9.5
Intestinal restoration
This product successfully restored my intestines in just a month. After suffering from dysbiosis following antibiotics, I now recommend it for bowel recovery. Taking it daily has made a significant difference in my health overall. If you find this helpful, please give a like!
9.5
Significant effect
After 20 years of irritable bowel syndrome, I found Bouladi. It remarkably lessened my symptoms, allowing me to manage my bolus without the usual urgency. This product has made a significant difference in my quality of life, providing a more relaxed experience.
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